Halotherapy relieves chronic obstructive pulmonary disease by alleviating NLRP3 inflammasome-mediated pyroptosis
Chenyan Zhang, Weijie Zhu, Qinghai Meng, Naqi Lian, Jingzhen Wu, Bowen Liu, Hao Wang, Xinyu Wang, Shujun Gu, Jingli Wen, Xiaoling Shen, Yu Li, Xu Qi
Annals of translational medicine · 2022 · China
Researchers studied lung function, oxidative stress and inflammatory signaling in a cigarette-smoke and lipopolysaccharide COPD model involving 120 rats.
Reported findings
Changes in lung function and inflammatory markers were accompanied by reduced activity in NLRP3-related signaling pathways in treated rats.
Limitations
- Animal research only—not a clinical trial and not evidence of effectiveness in humans.
- An induced rat disease model and experimental exposures cannot establish outcomes with consumer equipment.
Verification note
Published December 2022 and indexed in 2023. The publisher PDF and PMID 36618788 refer to one publication.
